Kentucky vs. Ole Miss prediction and betting tips - September 28 | College Football Week 5

The Kentucky Wildcats travel to Vaught-Hemingway Stadium in Oxford, Mississippi, on Saturday to face the No. 6 Ole Miss Rebels in a Week 5 SEC matchup.

The Wildcats are 2-2 through their first four games, coming off a dominant Week 4 win over Ohio. Kentucky topped the Bobcats 41-6 in their most complete showing of the season. The week before, Kentucky was just two points from upsetting the top-ranked Georgia Bulldogs.

Meanwhile, the Rebels enter Week 5 as one of the best teams in the land, with one of college football's strongest offenses. Ole Miss opens SEC play this weekend after taking down Furman, Middle Tennessee State, Wake Forest and Georgia Southern.

Here are official predictions and betting tips for this Week 5 contest.

Kentucky vs. Ole Miss: Prediction

The Kentucky Wildcats have shown the ability to play big on the big stage this season. Still, we will take Ole Miss in this Week 5 matchup for a few reasons.

While Kentucky nearly upset Georgia two weeks ago, the Wildcats were in Lexington. A week before that matchup, South Carolina routed Kentucky 31-6.

This weekend, the Wildcats face arguably the hottest offense in the country. Expect Jaxson Dart and company to maintain their fast start.

Kentucky vs. Ole Miss: Betting Tips

Tip 1: Ole Miss Rebels -17 (-110)

Tip 2: Total Points Over 52.5 (-110)

Tip 3: Jaxson Dart Over 2.5 Passing TDs (+115)

Kentucky vs. Ole Miss: Head-to-Head

Kentucky and Ole Miss have a storied rivalry that dates back to 1944 when the Wildcats defeated the Rebels 27-7 in Lexington.

Since then, Ole Miss and Kentucky have met 42 times, with Saturday marking the 44th game of the series. The Rebels lead the series 29-13. The teams tied in 1952.

Ole Miss has beaten the Wildcats three consecutive times and has won seven of its last ten games against Kentucky.