Iowa State vs. Iowa prediction & betting tips - September 7 | College Football Week 2

The CyHawk Series is getting ready to begin as the Iowa State Cyclones will travel to Kinnick Stadium on Saturday afternoon to take on the 21st-ranked Iowa Hawkeyes in non-conference action. The Cyclones are 1-0 this season after a 21-0 home win on Aug. 30 over the University of North Dakota Fighting Hawks.

The Hawkeyes are also 1-0 with a 40-0 home shutout victory against the Illinois State Redbirds on Aug. 30.

Let's take a closer look at this game to determine the best options for wagering.

Iowa State vs. Iowa prediction

The Iowa Hawkeyes have the more complete team and were able to showcase that in Week 1. With quarterback Cade McNamara healthy and looking impressive in his first game of the season, Iowa's offense is just on a completely different level than they were in the latter half of the 2023 season.

The Hawkeyes have a dominant defensive program that should slow down Iowa State's offense. Iowa allowed just 12 total first downs in Week 1 and forced three turnovers. While the Cyclones should be more competitive, Iowa should dominate in this game defensively.

However, as with many rivalry games, expect this to be close, but the Hawkeyes should take control late to win the game and cover the spread.

Iowa State vs. Iowa betting tips

Tip 1: Iowa Hawkeyes -3 (-105)

Tip 2: Iowa Hawkeyes Moneyline (-150)

Tip 3: Over 35.5 Points (-110)

Iowa State vs. Iowa head-to-head

These in-state rivals are certainly no strangers to one another as this Saturday's meeting will be the 71st time these programs play against each other. The Hawkeyes have controlled the all-time series with a 47-23 record, including winning the most recent game last season 20-13.

How to watch Iowa State vs. Iowa

The game between the Iowa State Cyclones and the Iowa Hawkeyes will be airing on CBS for network television and will be streamed on Paramount+, YouTube TV, Hulu + Live Sports and Sling.